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Research in type 2 diabetes animal models has demonstrated benefits for glucose control parameters and cardiovascular markers in laboratory investigations

Microinjection was performed using the following injection mix: KCl (25 mmol L 1 ), Hepes pH 7.4 (7.5 mmol L 1 ), tracrRNA (200 ng L 1 ), dpy-10 crRNA (150 ng L 1 ), dpy-10 ssODN (13.75 ng L 1 ), adh-5 sgRNA (300 ng L 1 ), adh-5 ssODN (100 ng L 1 ), Cas9 (416 ng L 1 , NEB, USA) 59

Furthermore, fecal EGCG was more abundant in HF+EGCG group, while gallic acid and epicatechin gallate were more abundant in the HF+GTE group

Hayward SW, Wang Y, Cao M, Hom YK, Zhang B, Grossfeld GD et al

Besides, previous works have demonstrated that patients with IBDs show an increased risk of developing colorectal cancer (CRC) [49], making the use of polyphenols a promising strategy to prevent and also aid in the management of this concern [50,51]